Aminobenzoic acids and derivatives
Cayman Chemical 16 16dimethyl Prostaglandin A
An inhibitor of HSV and HIV-1 viral replication; a metabolism resistant analog of PGA1; inhibits the viral replication of various strains of HSV-1 in Vero cells (ID50s = 3.8-5.6 UG/ml) and HIV-1 in human foreskin fibroblasts (ID50s = 4.6-7.3 UG/ml); inhibits acute HIV-1 infection in T cells (ID50 = 2.5 UG/ml)
Chemscene Metformin (hydrochloride) | 25g | CS-1851 | 98% | 1115-70-4 | MFCD00012582 | 165 62 | C4H12ClN5
Chemscene | Metformin (hydrochloride) | 25g | CS-1851 | 98% | 1115-70-4 | MFCD00012582 | 165 62 | C4H12ClN5
Chemscene Boc-L-Leu-OH | 100g | CS-W020087 | 97% | 13139-15-6 | MFCD00066067 | 231 29 | C11H21NO4
Chemscene | Boc-L-Leu-OH | 100g | CS-W020087 | 97% | 13139-15-6 | MFCD00066067 | 231 29 | C11H21NO4
Chemscene (2S)-2-[(tert-Butoxycarbonyl)amino]-3-(3-fluorophenyl)propionic acid | 25g | CS-0011430 | 95% | 114873-01-7 | MFCD00672522 | 283 30 | C14H18FNO4
Chemscene | (2S)-2-[(tert-Butoxycarbonyl)amino]-3-(3-fluorophenyl)propionic acid | 25g | CS-0011430 | 95% | 114873-01-7 | MFCD00672522 | 283 30 | C14H18FNO4
Chemscene 4-Bromo-7-methoxyquinoline | 5g | CS-W014665 | 98% | 1070879-27-4 | MFCD08063187 | 238 084 | C10H8BrNO
Chemscene | 4-Bromo-7-methoxyquinoline | 5g | CS-W014665 | 98% | 1070879-27-4 | MFCD08063187 | 238 084 | C10H8BrNO
Chemscene 6-(Ferrocenyl)hexanethiol | 1g | CS-0031519 | 95% | 134029-92-8 | MFCD09265168 | 302 26 | C16H22FeS
Chemscene | 6-(Ferrocenyl)hexanethiol | 1g | CS-0031519 | 95% | 134029-92-8 | MFCD09265168 | 302 26 | C16H22FeS
Medchemexpress LLC AC-186 | 1421854-16-1 | 99.6% | 306.32 | 1 MG
AC-186 is a selective non-steroidal estrogen receptor β (ERβ) agonist with EC50s of 6 nM and 5000 nM for ERβ and ERα, respectively. It has shown gender-selective neuroprotective effects in a male rat model of Parkinson's disease.
- Selective non-steroidal estrogen receptor β (ERβ) agonist.
- EC50s of 6 nM for ERβ and 5000 nM for ERα.
- Shows gender-selective neuroprotective effects in a male rat model of Parkinson's disease.
- Inhibits growth of LNCaP cells at 10 μM (72 h) and has no effect on PC3 cells.
- In vivo, 10 mg/kg (s.c.; once) prevented motor, cognitive, and sensorimotor gating deficits and mitigated the loss of dopamine neurons in the substantia nigra, in males, but not in females, in a male rat model of Parkinson's disease.
Chemscene 4-(Bromomethyl)-3-fluorobenzonitrile | 100g | CS-W001261 | 98% | 105942-09-4 | MFCD07368341 | 214 037 | C8H5BrFN
Chemscene | 4-(Bromomethyl)-3-fluorobenzonitrile | 100g | CS-W001261 | 98% | 105942-09-4 | MFCD07368341 | 214 037 | C8H5BrFN
Medchemexpress LLC Iristectorin A | 37744-61-9 | 1 MG
Iristectorin A is a natural product derived from *Iris tectorum* that exhibits anti-cancer activities in breast cancer.
Medchemexpress LLC N-(Amino-PEG1)-N-bis(PEG2-propargyl) | 2100306-47-4 | 98.0% | 356.46 | 50 MG
N-(Amino-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. This compound acts as a click chemistry reagent, featuring an alkyne group that can engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups. PROTACs themselves consist of two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein. PROTACs function by leveraging the intracellular ubiquitin-proteasome system for selective degradation of target proteins.
- Utilized in the synthesis of PROTACs
- Acts as a click chemistry reagent
- Features an alkyne group for copper-catalyzed azide-alkyne cycloaddition
- Engages with molecules containing azide groups
- PROTACs leverage the intracellular ubiquitin-proteasome system
- Enables selective degradation of target proteins
Chemscene 1-Bromo-2 4-dichlorobenzene | 100g | CS-W013035 | 98% | 1193-72-2 | MFCD00018333 | 225 9 | C6H3BrCl2
Chemscene | 1-Bromo-2 4-dichlorobenzene | 100g | CS-W013035 | 98% | 1193-72-2 | MFCD00018333 | 225 9 | C6H3BrCl2
Chemscene 3-Bromo-2-fluoro-5-(trifluoromethyl)pyridine | 25g | CS-W012749 | 98% | 1031929-01-7 | MFCD08061304 | 243 99 | C6H2BrF4N
Chemscene | 3-Bromo-2-fluoro-5-(trifluoromethyl)pyridine | 25g | CS-W012749 | 98% | 1031929-01-7 | MFCD08061304 | 243 99 | C6H2BrF4N
Chemscene Boc-L-Pyroglutamic acid methyl ester | 500g | CS-W003361 | 98% | 108963-96-8 | MFCD06809720 | 243 26 | C11H17NO5
Chemscene | Boc-L-Pyroglutamic acid methyl ester | 500g | CS-W003361 | 98% | 108963-96-8 | MFCD06809720 | 243 26 | C11H17NO5
Medchemexpress LLC (4E)-1,7-bis(4-hydroxy-3-methoxyphenyl)hept-4-en-3-one | 128700-97-0 | >95.0% | 1 ML
Gingerenone A is a diarylheptanoid research compound used as an Nrf2-Gpx4 activator and probe in studies of ferroptosis and inflammatory pathways. It is supplied as a ready-to-use 10 mM solution in DMSO (1 mL) and is also available in solid quantities for analytical and research applications.
- Natural diarylheptanoid with Nrf2-Gpx4 activity.
- Supplied as a 10 mM solution in DMSO, 1 mL, for immediate use.
- Also available in solid quantities for custom preparation.
- Molecular formula C21H24O5 and molecular weight 356.41.
- Intended for research use only; not for diagnostic or therapeutic use.
Cayman Chemical 16 16dimethyl Prostaglandin A
An inhibitor of HSV and HIV-1 viral replication; a metabolism resistant analog of PGA1; inhibits the viral replication of various strains of HSV-1 in Vero cells (ID50s = 3.8-5.6 UG/ml) and HIV-1 in human foreskin fibroblasts (ID50s = 4.6-7.3 UG/ml); inhibits acute HIV-1 infection in T cells (ID50 = 2.5 UG/ml)